Manufacturing Execution System (MES) Project of Zhongbang Pharmaceutical

I. Jiangsu Zhongbang Pharmaceutical: An Innovative Practitioner in the Pharmaceutical Industry

Jiangsu Zhongbang Pharmaceutical Co., Ltd. (hereinafter referred to as "Zhongbang Pharmaceutical") is a well-known enterprise in China’s pharmaceutical industry, focusing on the R&D, production, and sales of high-quality pharmaceuticals. Its products cover multiple therapeutic areas, including cardiovascular diseases, neurological diseases, and anti-infective drugs. With advanced production technology and a strict quality management system, Zhongbang Pharmaceutical has gained wide recognition in the domestic market and is gradually expanding into the international market.

However, as the enterprise scale continues to expand and market competition intensifies, the traditional production management model has gradually exposed many problems. Issues such as information silos in the production process, non-standard data management, and production efficiency bottlenecks have become key factors restricting the enterprise’s further development. To achieve sustainable development and enhance its core competitiveness, Zhongbang Pharmaceutical decided to introduce the advanced Xingdi MES System, initiating the digital transformation of production management.

II. MES System: A Key Step in Digital Transformation

Under the traditional production model, Zhongbang Pharmaceutical faced numerous challenges. Data recording in the production process relied on paper documents, which were not only prone to errors but also difficult to retrieve and analyze quickly. The operating status of on-site production equipment could not be monitored in real time, leading to frequent equipment failures that were hard to address promptly. Meanwhile, the disconnect between production plans and actual execution resulted in low production efficiency and severe resource waste. Additionally, quality traceability was difficult—once quality issues arose, it was hard to locate and resolve them quickly.

To solve these problems, Zhongbang Pharmaceutical decided to introduce the Hippocrates MES System, using digital means to improve the efficiency and transparency of production management. The Hippocrates  MES System organically integrates production equipment, materials, processes, and personnel, realizing information-based, automated, and intelligent management of the production process. Through data collection and analysis, the Hippocrates  MES System can monitor production status in real time, optimize production processes, improve product quality, reduce production costs, and bring comprehensive changes to the enterprise.

III. MES Project: Phased Implementation for Steady Progress

(I) Overall Planning Blueprint

Zhongbang Pharmaceutical’s MES project adopted the strategy of "overall planning and phased implementation" to ensure steady progress and successful delivery of the project.

1. Phase 1: System Planning and Infrastructure ConstructionThe project team conducted in-depth research on MES application cases of advanced enterprises at home and abroad, and formulated a detailed implementation plan based on Zhongbang Pharmaceutical’s actual needs. In this phase, the enterprise built the infrastructure of the Xingdi MES System, realized the initial connection between production equipment and the system, and laid the foundation for subsequent full-scale application.
2. Phase 2: Core Module Implementation and OptimizationIn this phase, the enterprise focused on implementing core modules such as production planning management, material management, and equipment monitoring. Through the Hippocrates  MES System, production plans could be issued to workshops in real time, the operating status of equipment was monitored in real time, and material flow was controlled accurately. At the same time, the system optimized production processes, reducing waiting time and resource waste in the production process.
3. Phase 3: Comprehensive Integration and In-depth ApplicationThe Hippocrates  MES System achieved comprehensive integration with the enterprise’s existing ERP, WMS, SCADA, and other systems, breaking down information silos and realizing seamless data sharing. By applying the data analysis function of the MES System in depth, the enterprise could grasp key indicators in the production process in real time, providing decision support for management. In addition, the MES System also realized full-process traceability of the production process, ensuring the traceability of product quality.

(II) Core Business Model

Centered on core modules such as production planning, material management, equipment monitoring, and data analysis, the MES project promoted the comprehensive upgrading of the enterprise’s production management.

• Production Planning ManagementBased on the enterprise’s production orders and resource conditions, the Hippocrates  MES System automatically generates the optimal production plan and issues it to workshops in real time. Through system monitoring, management can keep track of production progress at any time and adjust plans promptly to ensure the smooth completion of production tasks.
• Material ManagementThe Hippocrates MES System realizes precise management of materials. The entire process from raw material procurement to finished product storage is tracked and controlled through the system. The system automatically generates material balance and yield reports, reducing human errors and improving material utilization.
• Equipment Monitoring and OptimizationThe Hippocrates  MES System can monitor the operating status of all equipment in the factory in real time, detect equipment failures promptly, and issue alarms. Through the analysis of equipment operation curves, the enterprise can optimize production processes and improve equipment operation efficiency.
• Data Analysis and Decision SupportWith its powerful data analysis function, the Hippocrates  MES System provides real-time production data and key indicators for the enterprise’s management. Management can quickly understand production status through reports and dashboards generated by the system, making scientific decisions.

(III) Strong Technical Architecture Support

The Hippocrates MES System is built on an advanced digital platform, with high customization capabilities and efficient data access capabilities. Adopting a distributed architecture, the system optimizes data storage and access efficiency and can quickly respond to user query needs. At the same time, the Hippocrates  MES System supports integration with third-party systems, realizing data sharing and collaborative work across various business links within the enterprise.

IV. Significant Results: Comprehensively Enhancing Enterprise Competitiveness

(I) Internal Transformation of the Enterprise

The introduction of the Hippocrates MES System has brought significant internal changes to Zhongbang Pharmaceutical:

• Improved Production EfficiencyBy optimizing production processes and monitoring production status in real time, the Xingdi MES System has significantly improved the enterprise’s production efficiency. The execution of production plans is more accurate, equipment utilization has been greatly increased, and the production cycle has been shortened by more than 30%.
• Enhanced Quality ManagementThe MES System realizes full-process traceability of the production process and real-time monitoring of quality data, significantly improving product quality. The informatization rate of quality traceability has reached over 90%, and data consistency and integrity have reached 100%, earning the enterprise higher market trust.
• Optimized Resource AllocationThrough its data analysis function, the MES System helps the enterprise optimize resource allocation and reduce waste. The refinement of material management has increased the material utilization rate by 20% and reduced energy consumption by 15%.
• Paperless OfficeThe application of the MES System has realized paperless production management for the enterprise, reducing the cost of using and managing paper documents. At the same time, the system has improved data accuracy and security, avoiding errors in manual recording.

(II) Profound Social Impact

The successful implementation of Zhongbang Pharmaceutical’s MES project has not only brought significant benefits to the enterprise itself but also provided valuable experience for the digital transformation of the pharmaceutical industry:

• Industry Demonstration EffectAs an innovative practitioner in the pharmaceutical industry, Zhongbang Pharmaceutical’s successful case has demonstrated the great potential of the MES System in improving production management levels to peer enterprises, encouraging more enterprises to actively engage in digital transformation.
• Enhanced Quality AssuranceThrough the strict control of the MES System, the product quality of Zhongbang Pharmaceutical has been further improved, providing safer and more reliable pharmaceuticals for patients and safeguarding public health and well-being.
• Cost Reduction and Efficiency ImprovementThe application of the MES System has reduced the enterprise’s labor and management costs while improving production efficiency. The enterprise has invested the saved resources into R&D and innovation, further enhancing its core competitiveness.

V. Future Outlook: Continuous Innovation to Lead the Future with Intelligence

The successful implementation of the MES System has laid a solid foundation for Zhongbang Pharmaceutical’s digital transformation. However, the enterprise is well aware that digital transformation is a continuous process, and there is still broad room for development in the future.

• Continuous Optimization of System FunctionsZhongbang Pharmaceutical will continuously optimize the functions of the MES System according to the needs of business development. For example, it will further improve the equipment monitoring module to realize automatic diagnosis and predictive maintenance of equipment failures; it will optimize the production planning module to achieve more accurate production scheduling.
• Strengthening Data Analysis CapabilitiesThe enterprise will introduce more advanced data analysis technologies and tools to deeply mine production data in the MES System. Through the analysis of production data, the enterprise can predict potential problems in advance, optimize production processes, and further improve product quality.
• Exploring System Integration and CollaborationZhongbang Pharmaceutical will actively explore the integration of the MES System with other digital solutions. For example, integrating with intelligent manufacturing systems to realize intelligent control of the production process; integrating with supply chain management systems to realize collaborative production among upstream and downstream enterprises.
• Through these continuous efforts, Zhongbang Pharmaceutical will continue to move forward on the path of digital transformation, moving toward intelligence and high efficiency. This will not only help the enterprise stand out in the fierce market competition but also provide richer and more valuable experience for the digital transformation of the pharmaceutical industry, leading the industry toward a more brilliant future.

VI. Related Solutions

Solution 1: Intelligent Manufacturing Solution

VII. Related Cases

Case 1: MES System Project of Southwest Qizheng Pharmaceutical

Case 2: WMS System Project of Shanghai AdvaCare Pharmaceutical